Prof. Mario R. Capecchi PhD

Prof. Mario R. Capecchi PhD, was born in Verona, Italy, in 1937. He moved with his mother to the United States after the Second World War. Prof. Capecchi received his Bachelor of Science in chemistry and physics in 1961 from Antioch College in Ohio. Prof. Capecchi came to MIT (Massachuchetts Institute of Technology) as a graduate student intending to study physics and mathematics, but during the course of his studies, he became interested in molecular biology. He subsequently transferred to Harvard to join the lab of James D. Watson, co-discoverer of the structure of DNA. Prof. Capecchi received his PhD in biophysics in 1967 at the Harvard University, with his doctoral thesis completed under the tutelage of Watson. He was a Junior Fellow of the Society of Fellows at Harvard University from 1967 to 1969. In 1969 he became an Assistant Professor in the Department of Biochemistry at Harvard Medical School. He was promoted to Associate Professor in 1971. In 1973 he joined the faculty at the University of Utah. Prof. Capecchi has also been an investigator of the Howard Hughes Medical Institute since 1988.

He has won numerous awards, including the Kyoto Prize in Basic Sciences (1996), the Franklin Medal for Advancing Our Knowledge of the Physical Sciences (1997), the Feodor Lynen Lectureship (1998), the Rosenblatt Prize for Excellence (1998), the Baxter Award for Distinguished Research in the Biomedical Sciences (1998), the Helen Lowe Bamberger Colby and John E. Bamberger Presidential Endowed Chair in the University of Utah Health Sciences Center (1999), lectureship in the Life Sciences for the Collège de France (2000), the Horace Mann Distinguished Alumni Award, Antioch College (2000), the Italian Premio Phoenix-Anni Verdi for Genetics Research Award (2000), the March of Dimes Prize in Developmental Biology (2005).

Prof. Capecchi is known for his work on the development of gene targeting in embryo-derived stem cells of mice, creating mutations in any desired gene and giving freedom to manipulate the DNA sequence. In 2007 he won the Nobel Prize in physiology of medicine for this research, which he shared with prof. Oliver Smithies PhD and prof, Martin Evans PhD/His current research interests include the molecular genetic analysis of early mouse development and production of mouse models of human genetic diseases.

Prof. Cappecchis lecture will be about ‘Mouse Models of Human Disease from Cancer to Neuropsychiatric Disorders’. You can visit professor Capecchis lecture on the 5th of June from 09:15 till 10:15!